Ponce De Leon Hotel is centrally located in St. Petersburg, a 5-minute walk from Museum of Fine Arts and 6 minutes by foot from American Stage Theatre Company. This hotel is 0.4 mi (0.7 km) from University of South Florida-St. Petersburg and 0.5 mi (0.9 km) from 400 Beach.

Near Salvador Dali Museum Ponce De Leon Hotel is centrally located in St. Petersburg, a 5-minute walk from Museum of Fine Arts and 6 minutes by foot from American Stage Theatre Company. This hotel is 0.4 mi (0.7 km) from University of South Florida-St. Petersburg and 0.5 mi (0.9 km) from 400 Beach. Make yourself at home in one of the 74 air-conditioned rooms featuring flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls. Satisfy your appetite at Ceviche, a restaurant which features a bar/lounge. Dining is also available at the coffee shop/cafe.